Document Detail


The correlation of the D-dimer test and biphasic computed tomography with mesenteric computed tomography angiography in the diagnosis of acute mesenteric ischemia.
MedLine Citation:
PMID:  19324109     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Early diagnosis is the main factor to improve the outcome of acute mesenteric ischemia (AMI). The goal of this study was to assess the correlation of the D-dimer test and biphasic computed tomography (CT) with mesenteric CT angiography for the diagnosis of AMI. METHODS: Selected consecutive patients with a clinical suspicion of AMI were admitted to the study. Blood samples were taken before biphasic CT with mesenteric CT angiography examination. RESULTS: The sensitivity and specificity values of biphasic CT with mesenteric CT angiography were 92.9% and 89.5%, respectively. The sensitivity and specificity of D-dimer testing for the diagnosis of AMI were 94.7% and 78.6%, respectively. D-dimer levels higher than 3.17 microg fibrinogen equivalent units/mL were more specific (P < .0001) and acted similarly to the biphasic CT with mesenteric CT angiography in the diagnosis of AMI. CONCLUSIONS: In the setting of early diagnosis of AMI, the D-dimer test may improve our ability to diagnose patients in whom we cannot use multidetector row CT with CT angiography.
Authors:
Hizir Akyildiz; Alper Akcan; Ahmet Oztürk; Erdogan Sozuer; Can Kucuk; Ibrahim Karahan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  197     ISSN:  1879-1883     ISO Abbreviation:  Am. J. Surg.     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-27     Completed Date:  2009-04-14     Revised Date:  2009-05-20    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  429-33     Citation Subset:  AIM; IM    
Affiliation:
Department of General Surgery, School of Medicine, Erciyes University, Kayseri, Turkey. hyakyildiz@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Angiography
Fibrin Fibrinogen Degradation Products / diagnostic use
Humans
Mesenteric Vascular Occlusion / diagnosis*,  metabolism
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products; 0/fibrin fragment D

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