Document Detail

The coronary slow flow phenomenon: a new cardiac "Y" syndrome?
MedLine Citation:
PMID:  18503124     Owner:  NLM     Status:  MEDLINE    
The coronary slow flow phenomenon (CSFP) is an angiographic finding that is characterised by delayed progression of the contrast medium during coronary angiography. The mechanism of this phenomenon remains unknown. In the present paper, we revise the current evidence regarding this phenomenon and discuss recent findings from our group reporting increased resting resistances in patients with the CSFP. We report that these patients had preserved blood flow responses to the intracoronary infusion of the vasodilator papaverine, demonstrating that the CSFP is not necessarily associated with an abnormal coronary flow reserve. Based on these findings and on the review of the current literature, we concur with the concept proposed by Beltrame et al. that the CSFP should be considered a separate clinical entity. Further studies are necessary to describe the clinical characteristics, including the prognosis, of these patients and to identify potential treatments.
Maria Cristina Leone; Tommaso Gori; Massimo Fineschi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical hemorheology and microcirculation     Volume:  39     ISSN:  1386-0291     ISO Abbreviation:  Clin. Hemorheol. Microcirc.     Publication Date:  2008  
Date Detail:
Created Date:  2008-05-26     Completed Date:  2008-08-20     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9709206     Medline TA:  Clin Hemorheol Microcirc     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  185-90     Citation Subset:  IM    
Department of Internal Cardiovascular and Geriatric Medicine, and U.O.Emodinamica, University of Siena, Siena, Italy.
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MeSH Terms
Angiography / methods
Blood Flow Velocity
Cardiology / methods
Contrast Media / pharmacology
Coronary Angiography
Coronary Circulation
Coronary Vessels / pathology*
Heart Diseases / classification,  diagnosis*,  etiology*
Hemorheology / methods
Sex Factors
Reg. No./Substance:
0/Contrast Media

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