Document Detail

The coronary slow flow phenomenon--a new coronary microvascular disorder.
MedLine Citation:
PMID:  12145474     Owner:  NLM     Status:  MEDLINE    
The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease. Case-control and observational studies of patients with this phenomenon were conducted to determine the associated clinical features and prognosis. Patients with coronary slow flow (n = 47) differed from controls (n = 47), more often being current smokers (32 vs. 9%; p < 0.01) and presenting with rest pain requiring urgent admission (74 vs. 21%; p < 0.001), usually to the coronary care unit (66 vs. 17%; p < 0.01). During a median 21-month follow-up of 64 slow flow patients, 84% had recurrent chest pain. Based upon these findings and those of previous investigators, it is speculated that coronary slow flow is a new disease entity characterized by acute but recurrent perturbations of microvascular function.
John F Beltrame; Sananand B Limaye; John D Horowitz
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cardiology     Volume:  97     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  2002  
Date Detail:
Created Date:  2002-07-29     Completed Date:  2002-09-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  197-202     Citation Subset:  IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Cardiology Unit, North Western Adelaide Health Service, Queen Elizabeth Hospital Campus, Adelaide University, 28 Woodville Road, Woodville South, SA 5011, Australia.
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MeSH Terms
Blood Flow Velocity / physiology*
Case-Control Studies
Coronary Angiography
Coronary Circulation / physiology*
Coronary Disease / physiopathology*,  radiography
Coronary Vessels / physiopathology
Follow-Up Studies
Middle Aged
Ventricular Dysfunction, Left / physiopathology,  radiography
Comment In:
Cardiology. 2003;100(1):47   [PMID:  12975546 ]

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