Document Detail

A coronary active perfusion system for off-pump coronary artery bypass: advantage over passive perfusion regarding the physiology of the coronary artery.
MedLine Citation:
PMID:  12455779     Owner:  NLM     Status:  MEDLINE    
To avoid myocardial ischemia during off-pump coronary artery bypass, we developed a coronary active perfusion system (CAPS) that perfuses arterial blood to the coronary artery at the diastolic phase of the cardiac cycle by a syringe pump system. We report herein the details and compare CAPS with a passive shunt circuit from the femoral artery (FA shunt), regarding the physiology of the coronary artery. Six pigs were used for this study. After CAPS or FA shunt perfusion was established, coronary flow and coronary pressure were measured. The coronary flows in the native coronary artery, FA shunt perfusion, and CAPS perfusion with syringe pump stroke volume settings ranging from 0.1 to 0.4 ml were 27.2+/-3.0, 4.1+/-1.5, 12.7+/-1.2, 24.8+/-1.9, 33.3+/-1.6, and 42.2+/-1.9 ml/min, respectively. Mean coronary pressures under FA shunt perfusion and CAPS perfusion with stroke settings from 0.1 to 0.4 ml were 23.7+/-4.6, 48.8+/-5.0, 61.3+/-7.5, 70.8+/-5.4, and 82.3+/-5.2 mm Hg, respectively. CAPS had an advantage over the FA shunt regarding coronary flow with safe coronary pressure. Using CAPS, an off-pump coronary artery bypass can be performed safely without myocardial ischemia.
Hiroyuki Kamiya; Go Watanabe; Toshio Doi; Taro Saito; Masao Takahashi; Shigeyuki Tomita; Toshihide Tukioka; Taro Kanamori
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  48     ISSN:  1058-2916     ISO Abbreviation:  ASAIO J.     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2002-11-28     Completed Date:  2003-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  658-64     Citation Subset:  IM    
Department of General and Cardiothoracic Surgery, Kanazawa University Graduate School of Medicine, Japan.
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MeSH Terms
Anastomosis, Surgical / methods
Blood Pressure
Coronary Artery Bypass / instrumentation*,  methods*
Coronary Circulation / physiology*
Femoral Artery
Infusion Pumps
Myocardial Ischemia / prevention & control*
Pulsatile Flow / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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