Document Detail

The convergent and divergent validity of the Matson Evaluation of Drug Side-effects (MEDS) and the Dyskinesia Identification System: Condensed User Scale (DISCUS).
MedLine Citation:
PMID:  19039694     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Medication side-effects such as tardive dyskinesia (TD) are known to occur in individuals with a history of psychotropic drug use. This study aimed to contribute to the development of measures for assessing TD by examining the validity of the Matson Evaluation of Drug Side-effects (MEDS) with the Dyskinesia Identification System: Condensed User Scale (DISCUS) in 163 adults with intellectual disability (ID). METHOD: To establish convergent validity, the relationship between the MEDS and the DISCUS in identifying TD was examined. To establish divergent validity, the ability of the MEDS to differentiate between TD and other side-effects was investigated. RESULTS: The MEDS demonstrated convergent validity with the DISCUS on the Central Nervous System--Parkinsonism/Dyskinesia (CNS-PD) Subscale. The MEDS showed divergent validity with the DISCUS in cardiovascular and gastrointestinal side-effects, Parkinsonism symptoms (i.e., tremor, mask-like face), dystonia, and akathisia. DISCUSSION: The MEDS appears to have significant clinical utility in measuring tardive dyskinesia and other medication side-effects in individuals with ID.
Johnny L Matson; Jill C Fodstad; Tessa T Rivet
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Publication Detail:
Type:  Journal Article; Validation Studies    
Journal Detail:
Title:  Journal of intellectual & developmental disability     Volume:  33     ISSN:  1469-9532     ISO Abbreviation:  J Intellect Dev Disabil     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-28     Completed Date:  2009-04-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610837     Medline TA:  J Intellect Dev Disabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  337-44     Citation Subset:  IM    
Department of Psychology, Louisiana State University, Baton Rouge, LA 70803, USA.
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MeSH Terms
Aged, 80 and over
Dyskinesia, Drug-Induced / diagnosis*,  epidemiology,  psychology
Interview, Psychological / methods*,  standards*
Mental Retardation / drug therapy*,  epidemiology,  psychology
Middle Aged
Neurologic Examination / methods,  statistics & numerical data
Psychotropic Drugs / adverse effects*,  therapeutic use
Reproducibility of Results
Severity of Illness Index
Southeastern United States / epidemiology
Time Factors
Young Adult
Reg. No./Substance:
0/Psychotropic Drugs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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