Document Detail

A controlled comparison of symptoms and chemical intolerances reported by Gulf War veterans, implant recipients and persons with multiple chemical sensitivity.
MedLine Citation:
PMID:  10416290     Owner:  NLM     Status:  MEDLINE    
Using the Environmental Exposure and Sensitivity Inventory (EESI), a standardized instrument for measuring chemical sensitivity, we obtained and compared ratings of symptoms, chemical (inhalant) intolerances, other intolerances (e.g., drugs, caffeine, alcohol, skin contactants), lifeimpact, and masking (ongoing exposures) in five populations: multiple chemical sensitivity (MCS) patients who did (n = 96) or did not (n = 90) attribute onset of their illness to a specific exposure event, patients with implanted devices (n = 87), Gulf War veterans (n = 72), and controls (n = 76). For each patient group, mean scores on the first four scales were significantly greater than for controls. MCS patients reported avoiding more chemical exposures (were less masked) than the other groups. Across groups, for a given level of symptoms, as masking increased, mean scores on the Chemical Intolerance Scale decreased. In contrast, mean scores on the Other Intolerance Scale appeared to be less affected by masking. These findings suggest that some patients with antecedent chemical exposures, whether exogenous (chemical spill, pesticide application, indoor air contaminants) or endogenous (implant), develop new chemical, food, and drug intolerances. Reports of new caffeine, alcohol, medication, food, or other intolerances by patients may signal exposure-related illness. Masking may reduce individuals' awareness of chemical intolerances, and, to a lesser degree, other intolerances.
C S Miller; T J Prihoda
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Toxicology and industrial health     Volume:  15     ISSN:  0748-2337     ISO Abbreviation:  Toxicol Ind Health     Publication Date:    1999 Apr-Jun
Date Detail:
Created Date:  1999-09-20     Completed Date:  1999-09-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8602702     Medline TA:  Toxicol Ind Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  386-97     Citation Subset:  IM    
Department of Family Practice, University of Texas Health Science Center at San Antonio 78284-7794, USA.
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MeSH Terms
Environmental Exposure / adverse effects*
Middle Aged
Multiple Chemical Sensitivity / epidemiology*,  etiology*
Perceptual Masking / physiology*
Prostheses and Implants / adverse effects*
Quality of Life / psychology*

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