Document Detail

A controllable artificial afterload for isolated heart studies.
MedLine Citation:
PMID:  6503259     Owner:  NLM     Status:  MEDLINE    
This paper presents an artificial afterload, based on the Westerhof model, for use in isolated heart preparations. The system has adjustable elements representing peripheral resistance and total arterial compliance, together with a fixed element representing aortic impedance. It is controlled by a computer in a manner which incorporates feed forward and feedback techniques. The system maintains constant 'arterial' pressure in the face of large excursions of the flow through it. It can be programmed to change this pressure in a dynamic fashion. The time taken to recover from large changes in flow and to reset the pressure is at most 3 S. Absolute values of peripheral resistance are easily obtained without any knowledge of the actual flow being required. Tests of the system demonstrate its stability and rapid transient characteristics.
A Fisher; R E Challis; P Swann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biomedical engineering     Volume:  6     ISSN:  0141-5425     ISO Abbreviation:  J Biomed Eng     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1985-01-14     Completed Date:  1985-01-14     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  7906074     Medline TA:  J Biomed Eng     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  305-10     Citation Subset:  IM    
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MeSH Terms
Biomedical Engineering*
Heart, Artificial*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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