Document Detail

The control of large bowel cancers. Present status and it challenges.
MedLine Citation:
PMID:  1212647     Owner:  NLM     Status:  MEDLINE    
The incidence of carcinoma of the large bowel in the United States is higher than for any other site. In Japan it is about one quarter as frequent, and the cause of this discrepancy appears to be more environmental than genetic on the basis of migrant studies. The incidence of carcinoma in familial polyposis approaches 100% and in villous adenoma the incidence of carcinoma is 40-50%. The relation of adenomatous polyps to carcinoma is not so strong, yet there is a notable association between the occurrence of polyps and carcinoma in the same bowel. With modern surgical techniques, the risk of removing polypoid lesions of the colon transabdominally appears much lower than the average risk of leaving such lesions alone unless and until they give signs and symptoms of carcinoma. The greater use of the colonoscope should, however, greatly reduce the need for laparotomy.
J E Rhoads
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer     Volume:  36     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1975 Dec 
Date Detail:
Created Date:  1976-04-10     Completed Date:  1976-04-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2314-8     Citation Subset:  AIM; IM    
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MeSH Terms
Adenoma / prevention & control
Barium Sulfate / diagnostic use
Colitis, Ulcerative / surgery
Colonic Neoplasms / diagnosis,  genetics,  mortality,  prevention & control*,  surgery
Intestinal Polyps / genetics,  prevention & control
Precancerous Conditions / surgery
Rectal Neoplasms / diagnosis,  mortality,  prevention & control*,  surgery
Reg. No./Substance:
7727-43-7/Barium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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