Document Detail

The contribution of psychological factors to recovery after mild traumatic brain injury: Is cluster analysis a useful approach?
MedLine Citation:
PMID:  25409487     Owner:  NLM     Status:  Publisher    
Abstract Objectives: Outcomes after mild traumatic brain injury (MTBI) vary, with slow or incomplete recovery for a significant minority. This study examines whether groups of cases with shared psychological factors but with different injury outcomes could be identified using cluster analysis. Method: This is a prospective observational study following 147 adults presenting to a hospital-based emergency department or concussion services in Christchurch, New Zealand. This study examined associations between baseline demographic, clinical, psychological variables (distress, injury beliefs and symptom burden) and outcome 6 months later. A two-step approach to cluster analysis was applied (Ward's method to identify clusters, K-means to refine results). Results: Three meaningful clusters emerged (high-adapters, medium-adapters, low-adapters). Baseline cluster-group membership was significantly associated with outcomes over time. High-adapters appeared recovered by 6-weeks and medium-adapters revealed improvements by 6-months. The low-adapters continued to endorse many symptoms, negative recovery expectations and distress, being significantly at risk for poor outcome more than 6-months after injury (OR (good outcome) = 0.12; CI = 0.03-0.53; p < 0.01). Conclusions: Cluster analysis supported the notion that groups could be identified early post-injury based on psychological factors, with group membership associated with differing outcomes over time. Implications for clinical care providers regarding therapy targets and cases that may benefit from different intensities of intervention are discussed.
Deborah L Snell; Lois J Surgenor; E Jean C Hay-Smith; Jonathan Williman; Richard J Siegert
Related Documents :
3542917 - Differential response by adolescents to naproxen sodium therapy for spasmodic and conge...
24027727 - Granulocyte colony-stimulating factor for preterms with sepsis and neutropenia: a rando...
21896537 - Clinical trials update from the european society of cardiology heart failure meeting 20...
2499187 - A double-blind placebo-controlled comparison of the efficacy and safety of 50, 100, and...
17157117 - Clinical assessment of pain, tolerability, and preference of an autoinjection pen versu...
15272127 - Systemic inflammatory response depends on initial stroke severity but is attenuated by ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-19
Journal Detail:
Title:  Brain injury     Volume:  -     ISSN:  1362-301X     ISO Abbreviation:  Brain Inj     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-19     Completed Date:  -     Revised Date:  2014-11-20    
Medline Journal Info:
Nlm Unique ID:  8710358     Medline TA:  Brain Inj     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-9     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Next Document:  The alteration in placental volume and placental mean grey value in growth-restricted pregnancies as...