Document Detail


The contribution of peripheral chemoreceptors to ventilation during heavy exercise.
MedLine Citation:
PMID:  3602617     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to determine, in man, the contribution of peripheral chemoreceptors to ventilation during constant-load, heavy exercise above anaerobic threshold at sea level, using hyperoxic suppression of peripheral chemoreceptor drive which was obtained by abrupt and surreptitious replacement of inspired air with 100% oxygen for a period of 20-30 sec during the exercise. There was a delay of at least 1 sec from the time of peripheral chemoreceptor blockade to the initial change in ventilation, suggesting the operation of a central neural reverberatory mechanism after the cessation of peripheral chemoreceptor drive. In contrast to Wasserman (1976), whose results indicated a 25% decrease in ventilation within two breaths, in the present study no significant drop was observed until some 4-6 breaths after the air-to-oxygen switch. Furthermore, the drop in ventilation, magnitude of which was of the order of 15%, was transient in 5 out of 8 subjects. In one subject, the ventilation increased following oxygen administration. It is concluded that the peripheral chemoreceptors are not the sole mediators of hyperventilation of heavy exercise above anaerobic threshold in man.
Authors:
R Jeyaranjan; R Goode; S Beamish; J Duffin
Related Documents :
7789047 - Effects of inhaled nebulized morphine on ventilation and breathlessness during exercise...
3921517 - Respiratory, cardiovascular, and metabolic adjustments to exercise in the hereford calf.
15148837 - Nocturnal mechanical ventilation improves exercise capacity in kyphoscoliotic patients ...
3138747 - Possible gender differences in the effect of exercise on hypoxic ventilatory response.
9365347 - Reversal of antagonists: effect of elbow extension strength and endurance.
12383077 - Effect of hyperoxia on metabolic responses and recovery in intermittent exercise.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Respiration physiology     Volume:  68     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-08-04     Completed Date:  1987-08-04     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  203-13     Citation Subset:  IM; S    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acidosis / physiopathology
Adult
Anaerobiosis
Blood Circulation Time
Carotid Body / physiology
Chemoreceptor Cells / physiology*
Humans
Male
Oxygen / physiology
Physical Exertion*
Respiration*
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Characteristics of a simple measure of respiratory impedance.
Next Document:  Red cell age effects on metabolism and oxygen affinity in humans.