Document Detail


The contribution of pathological examination of the placenta in the investigation of the causes of foetal mortality.
MedLine Citation:
PMID:  8762882     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to evaluate the significance of histological examination of the placenta during routine post-mortem examination of foetal, perinatal and early neonatal deaths with particular reference to the cause of death. Three hundred (300) placentas were examinated over a period of three years (1988-1991). The clinical history, autopsy examination and placental histological examination were taken into account to determine the cause of death. Autopsy findings revealed the cause of death in only 33 cases (12.9%). In contrast, placental examination allowed us to determine the cause of death in 123 cases (48.4%) especially in abortions (54.4%). The most frequent abnormalities found were vascular insufficiency in intrauterine deaths (16.47%) and acute chorioamnionitis with foetal involvement in abortions (31.4%). Fifty six (56) cases with diagnoses of acute chorioamnionitis, chronic villitis of unknown aetiology and erythroblastosis were classified in the highrisk group for a subsequent pregnancy. Routine histological examination of the placenta following a perinatal death constitutes a necessary complement to autopsy examination, as it provides essential information for the cause of death and therefore helps in planning and more effective prenatal monitoring of a future pregnancy.
Authors:
E Agapitos; C Papadopoulou; N Kavantzas; J Papoulias; V Antonaki; P Davaris
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives d'anatomie et de cytologie pathologiques     Volume:  44     ISSN:  0395-501X     ISO Abbreviation:  Arch. Anat. Cytol. Pathol.     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-25     Completed Date:  1996-10-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7609770     Medline TA:  Arch Anat Cytol Pathol     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  5-11     Citation Subset:  IM    
Affiliation:
Service d'Anatomie Pathologique, Université d'Athènes, Grèce.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous
Amniotic Fluid / microbiology*
Bacterial Infections / complications,  diagnosis*
Cerebral Infarction / complications,  diagnosis*
Diseases in Twins / diagnosis
Female
Fetal Death / etiology*
Humans
Infant, Newborn
Myocardial Infarction / complications,  diagnosis*
Placenta Diseases / complications,  pathology*
Pregnancy
Pregnancy Complications, Cardiovascular
Pregnancy Complications, Infectious

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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