Document Detail


The contribution of the ossific nucleus to the structural stiffness of the capital femoral epiphysis: a porcine model for DDH.
MedLine Citation:
PMID:  10412989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The preosseous femoral head is thought to be vulnerable to compressive ischemic injury during the treatment of developmental dysplasia of the hip. The ossific nucleus has been proposed to increase the mechanical strength of the capital femoral epiphysis (CFE) and to decrease the risk of avascular necrosis. Sixty mixed-breed fetal and postgestational femoral head specimens were evaluated for structural stiffness in relation to the size of the ossific nucleus within the CFE. The structural stiffness of the CFE in the porcine model was found to increase exponentially with the size of the ossific nucleus. A finite-element model revealed that the presence of an ossific nucleus occupying 40% of the epiphyseal volume reduced the compressive strain in the region of the posterior-superior branch of the medial circumflex artery by an average of 54%. The results of this study support the hypothesis that the presence of the ossific nucleus may protect the CFE from compressive ischemic injury in the treatment of DDH.
Authors:
L S Segal; D J Schneider; J M Berlin; A Bruno; B R Davis; C R Jacobs
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Publication Detail:
Type:  Comparative Study; In Vitro; Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  19     ISSN:  0271-6798     ISO Abbreviation:  J Pediatr Orthop     Publication Date:    1999 Jul-Aug
Date Detail:
Created Date:  1999-09-14     Completed Date:  1999-09-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  433-7     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics and Rehabilitation, The Milton S. Hershey Medical Center and The Pennsylvania State University College of Medicine, Hershey 17033, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Biomechanics
Cell Nucleus / metabolism
Disease Models, Animal
Elasticity
Epiphyses / embryology,  pathology
Femur Head / embryology*,  pathology,  physiopathology*
Femur Head Necrosis / etiology,  pathology,  physiopathology*,  prevention & control*
Hip Dislocation, Congenital / pathology,  physiopathology*,  surgery
Osteoblasts / metabolism
Osteogenesis*
Sensitivity and Specificity
Stress, Mechanical
Swine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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