Document Detail

The contribution of functional neuroimaging to recovery after brain damage: a review.
MedLine Citation:
PMID:  11292157     Owner:  NLM     Status:  MEDLINE    
The introduction of functional neuroimaging techniques has contributed to understanding the neural correlates of recovery of motor, sensory and cognitive functions after brain damage. In this paper, we review the literature of the past twenty years, with particular emphasis on quantitative studies of cerebral blood flow and metabolism. Studies are presented that examine recovery from hemiparesis, aphasia, spatial hemineglect and sensory disorders. The contribution of this research is critically discussed in a methodological perspective. A basic distinction is made between cerebral plasticity and recovery of functions. It is also argued that the most frequently used experimental designs do not permit directly relating changes in brain activity to functional recovery. The importance of accurate behavioural measures is underlined. Alternative experimental designs are proposed, based on correlations between behavioural performance and brain activations.
L Pizzamiglio; G Galati; G Committeri
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cortex; a journal devoted to the study of the nervous system and behavior     Volume:  37     ISSN:  0010-9452     ISO Abbreviation:  Cortex     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-04-06     Completed Date:  2001-07-05     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0100725     Medline TA:  Cortex     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  11-31     Citation Subset:  IM    
Fondazione Santa Lucia, and Department of Psychology, Universita La Sapienza, Roma, Italy.
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MeSH Terms
Brain / pathology,  radiography,  radionuclide imaging
Brain Damage, Chronic / diagnosis*,  physiopathology*
Magnetic Resonance Imaging*
Recovery of Function
Tomography, Emission-Computed*
Tomography, Emission-Computed, Single-Photon*

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