| The continuing value of twin studies in the omics era. | |
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MedLine Citation:
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PMID: 22847273 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The classical twin study has been a powerful heuristic in biomedical, psychiatric and behavioural research for decades. Twin registries worldwide have collected biological material and longitudinal phenotypic data on tens of thousands of twins, providing a valuable resource for studying complex phenotypes and their underlying biology. In this Review, we consider the continuing value of twin studies in the current era of molecular genetic studies. We conclude that classical twin methods combined with novel technologies represent a powerful approach towards identifying and understanding the molecular pathways that underlie complex traits. |
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Authors:
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Jenny van Dongen; P Eline Slagboom; Harmen H M Draisma; Nicholas G Martin; Dorret I Boomsma |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-31 |
Journal Detail:
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Title: Nature reviews. Genetics Volume: - ISSN: 1471-0064 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-7-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100962779 Medline TA: Nat Rev Genet Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Biological Psychology, VU University, Van der Boechorststraat 1, 1081BT, Amsterdam, The Netherlands. |
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