Document Detail

A continuing outbreak of multidrug-resistant tuberculosis, with transmission in a hospital nursery.
MedLine Citation:
PMID:  9502446     Owner:  NLM     Status:  MEDLINE    
We investigated an increase in cases of multidrug-resistant tuberculosis (MDRTB) at a large urban facility where a prior nosocomial outbreak of MDRTB had occurred. Nosocomial transmission appeared to account for this outbreak as well, including a cluster of cases in a newborn nursery. Seven of 24 patients (29%) described in this investigation may have been exposed in the hospital nursery during an approximately 2-week period. We believe this to be the first documented outbreak of MDRTB in a hospital nursery. The transmission in the nursery demonstrates that the possibility of exposure to unrecognized active tuberculosis in nursery and hospital personnel is always present. Infection and active disease in the infants developed after a relatively short period of exposure. These findings underscore the need for adherence to published infection control guidelines in health care settings.
B Nivin; P Nicholas; M Gayer; T R Frieden; P I Fujiwara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  26     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-04-09     Completed Date:  1998-04-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  303-7     Citation Subset:  IM    
Bureau of Tuberculosis Control, New York City Department of Health, New York 10007, USA.
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MeSH Terms
Antitubercular Agents / pharmacology*
Cross Infection*
DNA, Bacterial / analysis
Disease Outbreaks*
Drug Resistance, Microbial
Drug Resistance, Multiple* / genetics
Health Facility Environment
Infant, Newborn
Microbial Sensitivity Tests
Nurseries, Hospital*
Tuberculosis / epidemiology,  microbiology,  transmission*
Reg. No./Substance:
0/Antitubercular Agents; 0/DNA, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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