Document Detail


The continuing increase in adenocarcinoma of the uterine cervix: a birth cohort phenomenon.
MedLine Citation:
PMID:  9119549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Adenocarcinoma of the uterine cervix has been reported to be increasing among young white women and earlier studies suggest a birth cohort pattern for the observed increase. No study, however, has examined the time trends of adenocarcinoma of the cervix by birth cohort. METHODS: Using Surveillance, Epidemiology, and End Results (SEER) data through 1990, the current study is designed to examine the time trends of invasive adenocarcinoma by birth cohort. An age-period-cohort model was fitted to the annual-age-specific rates to identify the components of birth cohort and time period as determinants of the observed time trends. RESULTS: The results from this study clearly show that invasive adenocarcinoma of the uterine cervix has been increasing in both whites and blacks, but the increase is statistically significant only among whites, reaching 4.2 percent per year for those born since 1935. The results also show that the recent increase in invasive adenocarcinoma started among those born around the mid 1920s, and a strong birth cohort effect is largely responsible for the observed increase. CONCLUSION: Invasive adenocarcinoma of the uterine cervix is increasing among recent birth cohorts. Analytical epidemiological studies are urgently needed to explore the risk factors responsible for the increase. The time trends for adenocarcinoma of the cervix should also be carefully monitored in the coming years.
Authors:
T Zheng; T R Holford; Z Ma; Y Chen; W Liu; B A Ward; P Boyle
Related Documents :
3931169 - Racial differences in the relation of birth weight and gestational age to neonatal mort...
18561009 - Timing of incarceration during pregnancy and birth outcomes: exploring racial differences.
3704839 - Neural tube defects among rural blacks in a transkei district. a preliminary report and...
7872039 - Suicide in south africa. an analysis of nationally registered mortality data for 1984-1...
9069019 - Adolescent pregnancy: understanding the impact of age and race on outcomes.
870659 - The dysmature infant. associated factors and outcome at 7 years of age.
7857959 - Effect of high-sugar intake by low-income pregnant adolescents on infant birth weight.
1183269 - Visual complexity in infancy: contour or numerosity?
2081789 - New uses of intravenous immune globulin in newborn infants.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  International journal of epidemiology     Volume:  25     ISSN:  0300-5771     ISO Abbreviation:  Int J Epidemiol     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1997-04-24     Completed Date:  1997-04-24     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  7802871     Medline TA:  Int J Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  252-8     Citation Subset:  IM    
Affiliation:
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520-8034, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / epidemiology*
Adult
African Americans
Age Distribution
Aged
Aged, 80 and over
Cohort Studies
European Continental Ancestry Group
Female
Humans
Incidence
Middle Aged
Regression Analysis
Risk Factors
SEER Program
United States / epidemiology
Uterine Cervical Neoplasms / epidemiology*
Grant Support
ID/Acronym/Agency:
CA-30931/CA/NCI NIH HHS; CA-62006 +/CA/NCI NIH HHS; CA-62986/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Reproducibility of a self-administered questionnaire for assessment of melanoma risk.
Next Document:  Perceived health status and morbidity and mortality: evidence from the Kuopio ischaemic heart diseas...