Document Detail


The continuing evolution of antiviral therapy for recurrent genital herpes: 1-day patient-initiated treatment with famciclovir.
MedLine Citation:
PMID:  18371288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Increased understanding of the clinical and virological characteristics of recurrent genital herpes simplex virus infection in healthy adults, recognition of the critical importance of early initiation of therapy, which is best achieved by self-initiated therapy, and an appreciation of the excellent tolerance and safety of relatively high doses of available antiviral drugs have facilitated refinements to treatment regimens that are more convenient as well as efficacious and well-tolerated. This paper reviews the progressive convergence of these concepts to an efficacious, well-tolerated, 1-day, patient-initiated regimen for treating episodes of recurrent genital herpes.
Authors:
Fred Y Aoki
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Herpes : the journal of the IHMF     Volume:  14     ISSN:  0969-7667     ISO Abbreviation:  Herpes     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-03-28     Completed Date:  2008-05-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9801722     Medline TA:  Herpes     Country:  England    
Other Details:
Languages:  eng     Pagination:  62-5     Citation Subset:  IM    
Affiliation:
University of Manitoba, Winnipeg, Manitoba, Canada. nelsonak@ms.umanitoba.ca
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MeSH Terms
Descriptor/Qualifier:
2-Aminopurine / administration & dosage,  analogs & derivatives*,  therapeutic use
Antiviral Agents / administration & dosage*,  therapeutic use
Female
Herpes Genitalis / drug therapy*,  prevention & control*,  virology
Herpesvirus 2, Human / drug effects
Humans
Randomized Controlled Trials as Topic
Recurrence
Self Administration
Time Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antiviral Agents; 104227-87-4/famciclovir; 452-06-2/2-Aminopurine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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