Document Detail


The context of a noxious stimulus affects the pain it evokes.
MedLine Citation:
PMID:  17449180     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of contextual factors on the pain evoked by a noxious stimulus is not well defined. In this study, a -20 degrees C rod was placed on one hand for 500 ms while we manipulated the evaluative context (or 'meaning') of, warning about, and visual attention to, the stimulus. For meaning, a red (hot, more tissue damaging) or blue (cold, less tissue damaging) visual cue was used. For warning, the stimulus occurred after the cue or they occurred together. For visual attention, subjects looked towards the stimulus or away from it. Repeated measures ANCOVA was significant (alpha=0.0125). Stimuli associated with a red cue were rated as hot, with the blue cue as cold (difference on an 11 point scale approximately 5.5). The red cue also meant the pain was rated as more unpleasant (difference approximately 3.5) and more intense (difference approximately 3). For stimuli associated with the red cue only, the pain was more unpleasant when the stimulus occurred after the cue than when it didn't (difference approximately 1.1). Pain was rated as more intense, and the stimulus as hotter, when subjects looked at the red-cued stimulus than when they didn't (difference approximately 0.9 for pain intensity and approximately 2 for temperature). We conclude that meaning affects the experience a noxious stimulus evokes, and that warning and visual attention moderate the effects of meaning when the meaning is associated with tissue-damage. Different dimensions of the stimulus' context can have differential effects on sensory-discriminative and affective-emotional components of pain.
Authors:
G Lorimer Moseley; Arnoud Arntz
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-04-20
Journal Detail:
Title:  Pain     Volume:  133     ISSN:  1872-6623     ISO Abbreviation:  Pain     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-27     Completed Date:  2008-01-31     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7508686     Medline TA:  Pain     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  64-71     Citation Subset:  IM    
Affiliation:
Department of Physiology, Anatomy & Genetics & fMRIB Centre, Le Gros Clark Building, Oxford University, South Parks Road, Oxford OX1 3QX, United Kingdom. lorimer.moseley@medsci.ox.ac.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Attention*
Cold Temperature / adverse effects
Conditioning, Classical
Confidence Intervals
Cues
Female
Humans
Male
Pain / etiology,  psychology*
Pain Measurement / psychology*
Pain Threshold / physiology
Pleasure-Pain Principle
Psychophysics
Temperature
Visual Perception / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Activation of the cortical pain network by soft tactile stimulation after injection of sumatriptan.
Next Document:  Analgesic properties of oleoylethanolamide (OEA) in visceral and inflammatory pain.