Document Detail

The conduction system in hearts with pulmonary atresia and intact ventricular septum.
MedLine Citation:
PMID:  12735569     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Although a regular course of the conduction system is anticipated in hearts with pulmonary atresia and intact ventricular septum (PAIVS), it has never been demonstrated anatomically. In view of one of the surgical options in repair being debulking of the right ventricular wall, it is important to establish the location of the major conduction pathways. METHODS: Four hearts belonging to fetuses aged 18, 20, 22, and 29 weeks were examined. Entire hearts were serially sectioned and step sections were stained. The sinus node and atrioventricular conduction bundles were identified and their locations described. RESULTS: The conduction system in hearts with PAIVS is similar to that in normal hearts, although there was a minor variation in one of them. This was a heart affected by Ebstein malformation of the tricuspid valve. In this case, the right bundle branch terminated abruptly soon after its origin. CONCLUSIONS: Confirmation of the regular course of the cardiac conduction system is important to the development of strategies for surgical repair of PAIVS.
Aneel Ansari; Diane Goltz; Karen Patricia McCarthy; Andrew Cook; Siew Yen Ho
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  75     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-08     Completed Date:  2003-05-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1502-5     Citation Subset:  AIM; IM    
Department of Paediatrics, Imperial College, Faculty of Medicine, London, United Kingdom.
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MeSH Terms
Ebstein Anomaly / embryology,  pathology
Fetus / pathology
Heart Conduction System / embryology,  pathology*
Heart Septum / embryology,  pathology*
Heart Ventricles / embryology
Pulmonary Atresia / complications,  embryology,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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