Document Detail


The conduction system in dilated cardiomyopathy. A pathomorphological study.
MedLine Citation:
PMID:  2816145     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A semi-serial histopathological study was conducted into the cardiac conduction system (CCS) of 14 autopsy subjects with dilated idiopathic cardiomyopathy (DIC). Clinical and pathomorphological data corresponding to this disease were compiled by Hudson's criteria. The most important histopathological findings were the frequency of vascular changes observed in small-size arteries that irrigate the sino-atrial and atrioventricular nodes, the bundle of His, the origin of both bundle branches, and the upper portion of the ventricular septum. Vascular changes, although unequal and inconstant, together with regressive and inflammatory features were observed in the majority of specimens. Also, good correlations were found to exist between electrocardiographic data and the direct cause of death, the intensity and/or extension of lesions did not correlate with the duration of the disease. While the vascular lesions might have been the first pathological changes, their variability and inconsistency suggested that more than one aetiological factors were involved in this type of cardiomyopathy.
Authors:
A Paramio; J E Fernández-Britto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zentralblatt für allgemeine Pathologie u. pathologische Anatomie     Volume:  135     ISSN:  0044-4030     ISO Abbreviation:  Zentralbl Allg Pathol     Publication Date:  1989  
Date Detail:
Created Date:  1989-12-20     Completed Date:  1989-12-20     Revised Date:  2014-09-18    
Medline Journal Info:
Nlm Unique ID:  9105593     Medline TA:  Zentralbl Allg Pathol     Country:  GERMANY, EAST    
Other Details:
Languages:  eng     Pagination:  631-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Atrioventricular Node / pathology
Bundle of His / pathology
Cardiomyopathy, Dilated / pathology*
Child, Preschool
Electrocardiography
Female
Heart Conduction System / pathology*
Heart Septum / pathology
Humans
Male
Middle Aged
Sinoatrial Node / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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