Document Detail

A concurrent epidemic of respiratory syncytial virus and echovirus 7 infections in an intensive care nursery.
MedLine Citation:
PMID:  2922234     Owner:  NLM     Status:  MEDLINE    
We describe concurrent outbreaks of respiratory syncytial virus (RSV) and Echovirus 7 (Echo 7) infections in a neonatal intensive care unit, including infants who had dual infections. Seventy-three infants were identified as having RSV from January through June, 1984. During the same surveillance period Echo 7 was cultured from 20 infants, and 6 infants had concurrent RSV and Echo 7 and RSV were isolated, but not concurrently. This dual outbreak of RSV and Echo 7 infections persisted for months despite infection control measures. Control procedures were complicated by: (1) cases of RSV infection at less than 72 hours of age, which had not previously been reported and which led to the reintroduction of RSV into "clean" areas; (2) the lack of a rapid diagnostic test for enterovirus infection; (3) the number of infants who were asymptomatic with each infection; and (4) the logistical problems of handling a dual pathogen outbreak in a confined setting. These problems were compounded by the many risk factors associated with nosocomial infections found in neonatal intensive care settings such as prolonged hospitalizations, endotracheal or nasogastric tubes and contact with many ancillary care personnel.
C W Wilson; D K Stevenson; A M Arvin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  8     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-04-19     Completed Date:  1989-04-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  24-9     Citation Subset:  IM    
Department of Pediatrics, Stanford University School of Medicine, CA 94305.
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MeSH Terms
Age Factors
Birth Weight
Cross Infection / epidemiology*
Disease Outbreaks*
Echovirus Infections / complications,  epidemiology*
Infant, Newborn
Intensive Care Units, Neonatal*
Respiratory Syncytial Viruses
Respirovirus Infections / complications,  epidemiology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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