| A computerized analysis of platelet aggregation detected by ultrasound. | |
| | |
MedLine Citation:
|
PMID: 2675387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The purpose of this study was to determine if computerized image processing could be used to characterize platelet aggregation visualized by ultrasound. Citrated whole blood (WB) or platelet-rich plasma (PRP) was imaged with a 12 mHz transducer before and after the addition of adenosine diphosphate. The images were digitized using a 512 x 512 pixel resolution with 256 levels of gray. Raster interference was eliminated by filtering and aggregates were separated from background by gray level discrimination. The results showed that platelet aggregation in PRP can be described by the number of aggregates counted, their sizes or their gray levels. However, aggregation in WB can be detected only by the sizes or gray levels of the aggregates due to the greater echogenicity of ex vivo WB. This methodology, applied to ultrasonic images of brachial arteries and veins, demonstrates that venous particles are common in patients and normal controls, but arterial particles are more common in patients. Differences in the size and brightness of these particles may have prognostic implications. |
| | |
Authors:
|
C Mahony; J L Elion; P L Fischer |
Related Documents
:
|
19794217 - Platelet-rich plasma: current concepts and application in sports medicine. 3088757 - Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregatio... 19371767 - Reduced platelet bdnf level in patients with major depression. 870397 - The role of factor xi in the coagulant activity of platelets. 8979317 - New insight into the mechanics of the lumbar interspinous ligament. 12626587 - Secretory phospholipases a2 activate selective functions in human eosinophils. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Thrombosis research Volume: 55 ISSN: 0049-3848 ISO Abbreviation: Thromb. Res. Publication Date: 1989 Aug |
Date Detail:
|
Created Date: 1989-10-16 Completed Date: 1989-10-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0326377 Medline TA: Thromb Res Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 351-60 Citation Subset: IM |
Affiliation:
|
Division of Cardiology, University of Kentucky School of Medicine, Lexington 40536. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arm
/
blood supply Brachial Artery Humans Image Processing, Computer-Assisted* Platelet Aggregation* Ultrasonography / methods* Veins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Biosynthesis of factor V by normal adult rat hepatocytes.
Next Document: Tetramine: occurrence in marine organisms and pharmacology.