| A computer-aided detection system for rheumatoid arthritis MRI data interpretation and quantification of synovial activity. | |
| | |
MedLine Citation:
|
PMID: 19411154 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
MATERIALS AND METHODS: 140 MRI scans from hands and wrists of 135 active RA patients and 5 healthy controls were processed using Dynamika-RA and evaluated with RAMRIS. To reduce patient motion artefacts, MRI data were processed using Dynamika-RA, which removed motion in 2D and 3D planes. Then synovial enhancement was visualised and qualified using a novel fully automated voxel-by-voxel analysis based algorithm. This algorithm was used to replace traditional region-of-interest (ROI) and subtraction methods, yielding observer independent quantitative results. RESULTS: Conventional scoring performed by an observer took 30-45 min per dataset. Dynamika-RA reduced motion artefacts, visualised inflammation and quantified disease activity in less than 3 min. Data processing allowed increasing signal to noise ratio by a factor 3. Due to fully automated procedure of data processing, there was no interest variation in the results. CONCLUSIONS: Algorithms incorporated into Dynamika-RA allow for the significant enhancement of data quality through eliminating motion artefacts and reduction of time for evaluation of synovial inflammation. |
| | |
Authors:
|
Olga Kubassova; Mikael Boesen; Marco A Cimmino; Henning Bliddal |
Related Documents
:
|
1739594 - Temporomandibular joint imaging. 22610534 - Ventilation imaging of the paranasal sinuses using xenon-enhanced dynamic single-energy... 1358334 - Computed tomography in diagnosis of septic sacroiliitis: report of three cases. 20578854 - Changes in temporomandibular joint disc position and form following herbst and fixed or... 6609384 - Pelvic radionuclide angiography in the diagnosis of gastrointestinal bleeding. 21405264 - Real time magnetic field sensing and imaging using a single spin in diamond. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-05-02 |
Journal Detail:
|
Title: European journal of radiology Volume: 74 ISSN: 1872-7727 ISO Abbreviation: Eur J Radiol Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-08-05 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
|
Languages: eng Pagination: e67-72 Citation Subset: IM |
Copyright Information:
|
Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Image Analysis Ltd., The Waterfront, Old Mill Lane, Saltaire BD17 7EZ, United Kingdom. olga@imageanalysis.org.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algorithms* Arthritis, Rheumatoid / diagnosis*, etiology Artificial Intelligence Female Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Magnetic Resonance Imaging / methods* Male Middle Aged Pattern Recognition, Automated / methods* Reproducibility of Results Sensitivity and Specificity Synovial Membrane / pathology* Synovitis / complications, diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Risk factors for protracted sinusitis in pediatrics after endoscopic sinus surgery.
Next Document: Identification and determination of the major constituents in Traditional Chinese Medicinal formula ...