| A computational pulsatile model of the bidirectional cavopulmonary anastomosis: the influence of pulmonary forward flow. | |
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MedLine Citation:
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PMID: 8950656 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The bidirectional cavopulmonary anastomosis (BCPA or bidirectional Glenn) is an operation to treat congenital heart diseases of the right heart by diverting the systemic venous return from the superior vena cava to both lungs. The main goal is to provide the correct perfusion to both lungs avoiding an excessive increase in systemic venous pressure. One of the factors which can affect the clinical outcome of the surgically reconstructed circulation is the amount of pulsatile blood flow coming from the main pulmonary artery. The purpose of this work is to analyse the influence of this factor on the BCPA hemodynamics. A 3-D finite element model of the BCPA has been developed to reproduce the flow of the surgically reconstructed district. Geometry and hemodynamic data have been taken from angiocardiogram and catheterization reports, respectively. On the basis of the developed 3-D model, four simulations have been performed with increasing pulsatile blood flow rate from the main pulmonary artery. The results show that hemodynamics in the pulmonary arteries are greatly influenced by the amount of flow through the native main pulmonary artery and that the flow from the superior vena cava allows to have a similar distribution of the blood to both lungs, with a little predilection for the left side, in agreement with clinical postoperative data. |
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Authors:
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F Migliavacca; M R de Leval; G Dubini; R Pietrabissa |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of biomechanical engineering Volume: 118 ISSN: 0148-0731 ISO Abbreviation: J Biomech Eng Publication Date: 1996 Nov |
Date Detail:
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Created Date: 1997-02-25 Completed Date: 1997-02-25 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7909584 Medline TA: J Biomech Eng Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 520-8 Citation Subset: IM |
Affiliation:
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Cardiothoracic Unit, Great Ormond Street Hospital for Children NHS Trust, London, U.K. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity Blood Pressure Computer Simulation Heart Bypass, Right* Heart Defects, Congenital / surgery* Hemodynamics Humans Models, Cardiovascular* Pulmonary Artery / physiopathology* Pulsatile Flow Vena Cava, Superior / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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