Document Detail

A comprehensive ethical framework for fetal research and its application to fetal surgery for spina bifida.
MedLine Citation:
PMID:  12114882     Owner:  NLM     Status:  MEDLINE    
The transition from innovation to standard of care for fetal surgery should be guided by ethical considerations. We provide an ethical framework that identifies criteria for the investigation of fetal surgery. This framework addresses the initiation and assessment of clinical trials to determine whether they establish a standard of care, describes an appropriate informed consent process, considers whether selection criteria should include the abortion preferences of the pregnant woman, and considers whether physicians have an obligation to offer referral to such investigation. This ethical framework, in a clinically comprehensive fashion, takes account of the physician's obligations to the fetal patient, the pregnant woman, and future fetal and pregnant patients. We apply this framework to clinical investigations of fetal surgery for spina bifida.
Frank A Chervenak; Laurence B McCullough
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  187     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-07-12     Completed Date:  2002-08-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10-4     Citation Subset:  AIM; E; IM    
Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY 10021, USA.
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MeSH Terms
Abortion, Induced
Clinical Trials as Topic / standards*
Ethics, Medical*
Fetal Diseases / surgery
Fetus / surgery*
Informed Consent
Research / standards
Spinal Dysraphism / surgery*
Comment In:
Am J Obstet Gynecol. 2003 Mar;188(3):854-5; author reply 855-6   [PMID:  12634670 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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