| A comprehensive ethical framework for fetal research and its application to fetal surgery for spina bifida. | |
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MedLine Citation:
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PMID: 12114882 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The transition from innovation to standard of care for fetal surgery should be guided by ethical considerations. We provide an ethical framework that identifies criteria for the investigation of fetal surgery. This framework addresses the initiation and assessment of clinical trials to determine whether they establish a standard of care, describes an appropriate informed consent process, considers whether selection criteria should include the abortion preferences of the pregnant woman, and considers whether physicians have an obligation to offer referral to such investigation. This ethical framework, in a clinically comprehensive fashion, takes account of the physician's obligations to the fetal patient, the pregnant woman, and future fetal and pregnant patients. We apply this framework to clinical investigations of fetal surgery for spina bifida. |
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Authors:
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Frank A Chervenak; Laurence B McCullough |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 187 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2002 Jul |
Date Detail:
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Created Date: 2002-07-12 Completed Date: 2002-08-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 10-4 Citation Subset: AIM; E; IM |
Affiliation:
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Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY 10021, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced Clinical Trials as Topic / standards* Ethics, Medical* Female Fetal Diseases / surgery Fetus / surgery* Humans Informed Consent Pregnancy Research / standards Spinal Dysraphism / surgery* |
| Comments/Corrections | |
Comment In:
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Am J Obstet Gynecol. 2003 Mar;188(3):854-5; author reply 855-6
[PMID:
12634670
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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