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The complex world of kidney microRNAs.
MedLine Citation:
PMID:  21799505     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
MicroRNAs are short noncoding RNAs that usually reduce translation of messenger RNAs. Changes in microRNA-192 (miR-192) are reported in states of renal fibrosis. New evidence supports a role for miR-192 and its target miR-200b/c in transforming growth factor-β1 regulation of its own expression and that of collagens in mesangial cells, with a possible role in diabetic nephropathy. As there is controversy on the role of these microRNAs in diabetic nephropathy, more work is needed.
Authors:
Balakuntalam S Kasinath; Denis Feliers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kidney international     Volume:  80     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  334-7     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Texas Health Science Center, South Texas Veterans Health Care System, San Antonio, Texas, USA.
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