Document Detail


A complete mock circulation loop for the evaluation of left, right, and biventricular assist devices.
MedLine Citation:
PMID:  15982285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new mock circulation loop was developed to replicate the necessary features of the systemic and pulmonic circulatory systems, including pulsatile left and right ventricles coupled with vascular compliances and resistances. A brief description of the mock loop construction is provided before results are presented confirming the recreation of perfusion rates and pressures found in the natural systemic and pulmonic vascular trees for a normal and failing heart at rest. This rig provides the ability to evaluate the hemodynamic effect of left, right, and biventricular assist devices in vitro. The small and compact mock circulation rig has the potential to reduce device evaluation costs by simulating the natural circulatory system, thus providing valuable device performance feedback prior to expensive in vivo animal trials.
Authors:
Daniel Timms; Mark Hayne; Keith McNeil; Andrew Galbraith
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Artificial organs     Volume:  29     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-06-28     Completed Date:  2005-11-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  564-72     Citation Subset:  IM    
Affiliation:
Queensland University of Technology, Brisbane, Queensland, Australia. d.timms@qut.edu.au
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MeSH Terms
Descriptor/Qualifier:
Blood Circulation / physiology*
Blood Pressure / physiology
Cardiovascular System / physiopathology*
Equipment Design
Equipment Failure Analysis
Extracorporeal Circulation / instrumentation*
Heart Failure / physiopathology*
Heart-Assist Devices
Hemorheology
Humans
Models, Cardiovascular
Vascular Resistance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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