Document Detail

A comparison of transesophageal echocardiography and transcranial Doppler sonography with contrast medium for detection of patent foramen ovale.
MedLine Citation:
PMID:  7911265     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Patent foramen ovale as a possible stroke risk factor can be diagnosed with transcranial Doppler sonography (TCD) by detecting intravenous contrast medium crossing from the right to the left atrium. The present study evaluates the reliability of this method. SUMMARY OF REPORT: We performed TCD and transesophageal echocardiography simultaneously in 50 patients using galactose microbubbles. We observed bubble signals passing the middle cerebral artery in 7 patients less than 20 seconds after injection; we found positive TCD tests in 14 patients using the Valsalva maneuver. With transesophageal echocardiography patent foramen ovale could be detected in 15 patients (sensitivity, 0.93; specificity, 1; P < .01). CONCLUSIONS: TCD with echo contrast is a reliable screening tool for patent foramen ovale. A standardized procedure including the Valsalva maneuver is essential to prevent false-negative results.
M Jauss; M Kaps; M Keberle; W Haberbosch; W Dorndorf
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  25     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-07-01     Completed Date:  1994-07-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1265-7     Citation Subset:  IM    
Department of Neurology, University of Giessen, Germany.
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MeSH Terms
Cerebral Arteries / ultrasonography*
Cerebrovascular Disorders / ultrasonography
Contrast Media*
Echocardiography, Doppler
Echocardiography, Transesophageal*
Galactose / diagnostic use
Heart Atria / ultrasonography
Heart Septal Defects, Atrial / ultrasonography*
Ischemic Attack, Transient / ultrasonography
Middle Aged
Prospective Studies
Time Factors
Ultrasonography, Doppler, Transcranial*
Valsalva Maneuver
Reg. No./Substance:
0/Contrast Media; 26566-61-0/Galactose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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