| A comparison of topical acyclovir with steroids in the treatment of herpes zoster keratouveitis. | |
| | |
MedLine Citation:
|
PMID: 6357273 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Topical acyclovir has been compared with topical steroids in a coded controlled trial of the treatment of keratouveitis caused by herpes zoster in 40 patients. Topical acyclovir was significantly superior to topical steroids in terms of treatment duration (75 days to 280 days), with no recurrences after the patients were weaned off treatment; there was a 63% recurrence rate in the steroid group. Corneal epithelial disease resolved significantly quicker in the acyclovir treated group. If recurrences occurred in the steroid group, other parts of the eye not initially affected were also involved. Treatment of such recurrences was more difficult than treatment of the initial attack. |
| | |
Authors:
|
J McGill; C Chapman |
Related Documents
:
|
19885903 - Exogenous alkaline phosphatase for the treatment of patients with moderate to severe ul... 17112853 - Conversion from azathioprine to mycophenolate mofetil followed by calcineurin inhibitor... 17879083 - Treatment of midportion achilles tendinosis: similar clinical results with us and cd-gu... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: The British journal of ophthalmology Volume: 67 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 1983 Nov |
Date Detail:
|
Created Date: 1984-01-07 Completed Date: 1984-01-07 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 746-50 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acyclovir
/
therapeutic use* Administration, Topical Aged Betamethasone / therapeutic use* Clinical Trials as Topic Double-Blind Method Female Herpes Zoster Ophthalmicus / drug therapy* Humans Keratitis / drug therapy* Male Recurrence Uveitis / drug therapy* |
| Chemical | |
Reg. No./Substance:
|
378-44-9/Betamethasone; 59277-89-3/Acyclovir |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A randomized trial of weekly cardiotocography in high-risk obstetric patients.
Next Document: Retraction of canines using bonded tube-brackets.