Document Detail


A comparison of target-controlled therapy with patient-controlled administration of propofol combined with midazolam for sedation during dental surgery.
MedLine Citation:
PMID:  12622106     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty anxious day case patients undergoing extraction of third molar teeth under local anaesthesia with sedation, were studied in a randomised double-blind controlled trial. A target-controlled infusion of propofol was compared with patient-controlled propofol for sedation, combined with a small dose of midazolam to improve amnesia. The objectives of the study were to measure the total dose of propofol used by the two groups and assess recovery and patient satisfaction. The mean dose of propofol used in the patient-controlled sedation group was significantly less than the target-controlled group (p < 0.00007). Five patients became over-sedated in the target-controlled group compared with none in the patient-controlled group. Only one of the three tests of performance showed that the target-controlled patients were more sedated. Patient satisfaction was high in both groups despite a greater recollection of events in the patient-controlled group.
Authors:
R Burns; A F McCrae; B Tiplady
Related Documents :
15449916 - Patient controlled intravenous analgesia (pcia) in postoperative surgical patients: an ...
22985236 - Eating disorders and pathological gambling in males: can they be differentiated by mean...
15259516 - Comparison of fentanyl versus meperidine for analgesia in pediatric gastrointestinal en...
2134446 - Results of hypotensive anesthesia in operative treatment of thoracolumbar fractures.
3606286 - Secondary hypertension in a blood pressure clinic.
1416436 - The role of laparoscopy in the diagnosis of acute appendicitis.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia     Volume:  58     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-03-06     Completed Date:  2003-03-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  170-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Anaesthetics, Royal Infirmary of Edinburgh, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Ambulatory Surgical Procedures
Anesthesia, Dental / methods*
Anesthesia, Local
Conscious Sedation / methods*
Double-Blind Method
Drug Combinations
Female
Hemodynamics / drug effects
Humans
Hypnotics and Sedatives*
Male
Midazolam*
Molar, Third / surgery
Patient Satisfaction
Propofol*
Self Administration
Tooth Extraction*
Chemical
Reg. No./Substance:
0/Drug Combinations; 0/Hypnotics and Sedatives; 2078-54-8/Propofol; 59467-70-8/Midazolam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The need for a regional weaning centre, a one-year survey of intensive care weaning delay in the Nor...
Next Document:  White cell count and intensive care unit outcome.