Document Detail

A comparison of the recovery characteristics of sevoflurane and halothane in children.
MedLine Citation:
PMID:  8694205     Owner:  NLM     Status:  MEDLINE    
The recovery characteristics of sevoflurane and halothane anaesthesia were compared in 40 children aged 6 months to 6 years undergoing day case surgery. The mean time taken to open eyes after surgery had ended was appreciably and significantly shorter after sevoflurane than after halothane (sevoflurane, mean time (SD) 7 min 52 s (5 min 46 s), halothane, mean time (SD) 15 min 50 s (9 min 2 s), t = 3.32, p = 0.002). The time taken to be ready for discharge from the recovery unit to the ward was also significantly shorter after sevoflurane than after halothane (sevoflurane, mean time (SD) 12 min 46 s (4 min 11 s), halothane, mean time (SD) 19 min 13 s (9 min 48 s), t = 2.7, p < 0.01). However, more children were in pain and given analgesia after sevoflurane (p < 0.01) and the mean time to reach the criteria for discharge home was similar in both groups (sevoflurane, mean time (SD) 2 h 9 min (17 min), halothane, mean time (SD) 2 h 4 min (8 min)). There were no major complications in either group.
M R Sury; A Black; L Hemington; R Howard; D J Hatch; A Mackersie
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Publication Detail:
Type:  Clinical Trial; Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia     Volume:  51     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-08-26     Completed Date:  1996-08-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  543-6     Citation Subset:  AIM; IM    
Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, London.
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MeSH Terms
Ambulatory Surgical Procedures*
Anesthesia Recovery Period
Anesthesia, Inhalation / methods
Anesthetics, Inhalation*
Child, Preschool
Methyl Ethers*
Pain, Postoperative
Time Factors
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Ethers; 0/Methyl Ethers; 151-67-7/Halothane; 28523-86-6/sevoflurane

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