Document Detail


A comparison of prophylactic ondansetron hydrochloride and droperidol for strabismus repair in adults.
MedLine Citation:
PMID:  9782437     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Prophylactic administration of an antiemetic is a common procedure for patients undergoing strabismus surgery. Droperidol and ondansetron hydrochloride are commonly used antiemetics. This study compared the rates of postoperative nausea and vomiting (PONV) in adult patients undergoing strabismus surgery with prophylactically administered Droperidol or ondansetron hydrochloride. METHODS: A double-masked, randomized, prospective study was conducted comparing droperidol with ondansetron hydrochloride when administered prophylactically to adults undergoing strabismus surgery. RESULTS: Forty-five patients entered the study with a mean age of 30 years. Twenty percent of patients had nausea immediately postoperatively and 37% had nausea before discharge with no significant differences between groups. Overall rate of emesis, time in the recovery room, and time to discharge was not significantly different between the droperidol and ondansetron hydrochloride group. CONCLUSION: No real differences in the ability to prevent PONV between the two medications were found in this study.
Authors:
E A Doe; P Jones; M A O'Hara
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of pediatric ophthalmology and strabismus     Volume:  35     ISSN:  0191-3913     ISO Abbreviation:  J Pediatr Ophthalmol Strabismus     Publication Date:    1998 Sep-Oct
Date Detail:
Created Date:  1998-12-15     Completed Date:  1998-12-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7901143     Medline TA:  J Pediatr Ophthalmol Strabismus     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  264-9; 286-7     Citation Subset:  IM    
Affiliation:
Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Antiemetics / therapeutic use*
Double-Blind Method
Droperidol / therapeutic use*
Follow-Up Studies
Humans
Middle Aged
Nausea / prevention & control*
Ondansetron / therapeutic use*
Postoperative Complications / prevention & control
Prospective Studies
Strabismus / surgery*
Treatment Outcome
Vomiting / prevention & control*
Chemical
Reg. No./Substance:
0/Antiemetics; 548-73-2/Droperidol; 99614-02-5/Ondansetron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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