Document Detail


A comparison of phonological skills of boys with fragile X syndrome and Down syndrome.
MedLine Citation:
PMID:  16411789     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, the authors compared the phonological accuracy and patterns of sound change of boys with fragile X syndrome, boys with Down syndrome, and typically developing mental-age-matched boys. Participants were 50 boys with fragile X syndrome, ages 3 to 14 years; 32 boys with Down syndrome, ages 4 to 13 years; and 33 typically developing boys, ages 2 to 6 years, who were matched for nonverbal mental age to both the boys with fragile X syndrome and the boys with Down syndrome. All participants were administered a standardized articulation test, and their sound accuracy, phonological process, and proportion of whole-word proximity scores were analyzed. Although boys with fragile X syndrome were delayed in their speech development, they did not differ from the typically developing, mental-age-matched boys in the percentage of correct early-, middle-, and late-developing consonants; phonological processes; or whole-word proximity scores. Furthermore, boys with fragile X syndrome had fewer errors on early-, middle-, and late-developing consonants; fewer syllable structure processes; and higher whole-word proximity scores than did boys with Down syndrome. Boys with Down syndrome also were delayed in their speech development, yet their phonological inventories, occurrences of phonological processes, and proportion of whole-word proximity scores indicated greater delays in their phonological development than the younger, typically developing boys. These results suggest that males with fragile X syndrome display phonological characteristics in isolated words similar to younger, typically developing children, whereas males with Down syndrome show greater delays as well as some developmental differences compared with both the males with fragile X syndrome and typically developing males.
Authors:
Joanne Roberts; Steven H Long; Cheryl Malkin; Elizabeth Barnes; Martie Skinner; Elizabeth A Hennon; Kathleen Anderson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of speech, language, and hearing research : JSLHR     Volume:  48     ISSN:  1092-4388     ISO Abbreviation:  J. Speech Lang. Hear. Res.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2006-01-17     Completed Date:  2006-07-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9705610     Medline TA:  J Speech Lang Hear Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  980-95     Citation Subset:  IM    
Affiliation:
Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, USA. joanne_roberts@unc.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Analysis of Variance
Case-Control Studies
Child
Child, Preschool
Down Syndrome / complications*,  physiopathology
Fragile X Syndrome / complications*,  physiopathology
Humans
Male
Phonetics*
Speech Disorders / etiology*,  physiopathology
Speech Production Measurement
Verbal Behavior
Grant Support
ID/Acronym/Agency:
1 R01 HD044935/HD/NICHD NIH HHS; 1 R01 HD38819/HD/NICHD NIH HHS; 1 R03 HD40640/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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