Document Detail


A comparison of the influence of global functional loads vs. local contact anatomy on articular cartilage thickness at the knee.
MedLine Citation:
PMID:  17418219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cartilage contact geometry, along with joint loading, can play an important role in determining local articular cartilage tissue stress. Thus individual variations in cartilage thickness can be associated with both individual variations in joint loading associated with activities of daily living as well as individual differences in the anatomy of the contacting surfaces of the joint. The purpose of this study was to isolate the relationship between cartilage thickness predicted by individual variations in contact surface geometry based on the radii of the femur and tibia vs. cartilage thickness predicted by individual variations in joint loading. Knee magnetic resonance (MR) images and the peak knee adduction moments during walking were obtained from 11 young healthy male subjects (age 30.5+/-5.1 years). The cartilage thicknesses and surface radii of the femoral and tibial cartilage were measured in the weight-bearing regions of the medial and lateral compartments of three-dimensional models from the MR images. The ratio of contact pressure between the medial and lateral compartments was calculated from the radii of tibiofemoral contact surface geometries. The results showed that the medial to lateral pressure ratios were not correlated with the medial to lateral cartilage thickness ratios. However, in general, pressure was higher in the lateral than medial compartments and cartilage was thicker in the lateral than medial compartments. The peak knee adduction moment showed a significant positive linear correlation with medial to lateral thickness ratio in both femur (R(2)=0.43,P<0.01) and tibia (R(2)=0.32,P<0.01). The results of this study suggest that the dynamics of walking is an important factor to describe individual differences in cartilage thickness for normal subjects.
Authors:
Seungbum Koo; Thomas P Andriacchi
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2007-04-05
Journal Detail:
Title:  Journal of biomechanics     Volume:  40     ISSN:  0021-9290     ISO Abbreviation:  J Biomech     Publication Date:  2007  
Date Detail:
Created Date:  2007-09-07     Completed Date:  2007-11-09     Revised Date:  2014-09-11    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2961-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Cartilage, Articular / anatomy & histology*
Humans
Knee / anatomy & histology*
Male
Stress, Mechanical
Weight-Bearing / physiology
Grant Support
ID/Acronym/Agency:
R01 AR 049792-04/AR/NIAMS NIH HHS; R01 AR049792/AR/NIAMS NIH HHS; R01 AR049792-04/AR/NIAMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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