Document Detail

A comparison of haemodynamic response with pethidine vs. butorphanol in open cholecystectomy cases.
MedLine Citation:
PMID:  15821379     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The present study was undertaken to compare the haemodynamic responses with pethidine vs. Butorphanol intraoperatively in open cholecystectomy cases in KMCTH. METHOD: In this randomized study, all together 40 patients undergoing routine cholecystectomy surgery were included. Group A received Pethidine 1 mg/kg and Group B received Butorphanol 0.04 mg/kg intraoperatively. Heart rate and blood pressure were recorded before injection of the drug, after injection, before intubation, after intubation, before skin incision, after incision, before extubation and after extubation data analysis was done using independent sample t test. RESULT: Our study showed no statistical significance in haemodynamic responses with either pethidine or Butorphanol in open cholecystectomy cases. CONCLUSION: Both drugs appear equally good analgesics in our study.
S Tabedar; S K Maharjan; B R Shrestha; S Shrestha
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Kathmandu University medical journal (KUMJ)     Volume:  2     ISSN:  1812-2027     ISO Abbreviation:  -     Publication Date:    2004 Apr-Jun
Date Detail:
Created Date:  2005-04-11     Completed Date:  2005-04-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101215359     Medline TA:  Kathmandu Univ Med J (KUMJ)     Country:  Nepal    
Other Details:
Languages:  eng     Pagination:  127-30     Citation Subset:  IM    
Department of Anaesthesiology, Kathmandu Medical College, Sinamangal, KTM.
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MeSH Terms
Adjuvants, Anesthesia / pharmacology*
Analgesics, Opioid / pharmacology*
Blood Pressure / drug effects*
Butorphanol / pharmacology*
Heart Rate / drug effects*
Intraoperative Period
Meperidine / pharmacology*
Middle Aged
Reg. No./Substance:
0/Adjuvants, Anesthesia; 0/Analgesics, Opioid; 42408-82-2/Butorphanol; 57-42-1/Meperidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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