Document Detail


A comparison of exercise type and intensity on the noninvasive assessment of skeletal muscle mitochondrial function using near-infrared spectroscopy.
MedLine Citation:
PMID:  23154991     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Near-infrared spectroscopy (NIRS) can be used to measure muscle oxygen consumption (mVO(2)) using arterial occlusions. The recovery rate of mVO(2) after exercise can provide an index of skeletal muscle mitochondrial function. The purpose of this study was to test the influence of exercise modality and intensity on NIRS measurements of mitochondrial function. Three experiments were performed. Thirty subjects (age: 18-27 yr) were tested. NIRS signals were corrected for blood volume changes. The recovery of mVO(2) after exercise was fit to a monoexponential curve, and a rate constant was calculated (directly related to mitochondrial function). No differences were found in NIRS rate constants for VOL and ES exercises (2.04 ± 0.57 vs. 2.01 ± 0.59 min(-1) for VOL and ES, respectively; P = 0.317). NIRS rate constants were independent of the contraction frequency for both VOL and ES (VOL: P = 0.166 and ES: P = 0.780). ES current intensity resulted in significant changes to the normalized time-tension integral (54 ± 11, 82 ± 7, and 100 ± 0% for low, medium, and high currents, respectively; P < 0.001) but did not influence NIRS rate constants (2.02 ± 0.54, 1.95 ± 0.44, 2.02 ± 0.46 min(-1) for low, medium, and high currents, respectively; P = 0.771). In summary, NIRS measurements of skeletal muscle mitochondrial function can be compared between VOL and ES exercises and were independent of the intensity of exercise. NIRS represents an important new technique that is practical for testing in research and clinical settings.
Authors:
Terence E Ryan; Jared T Brizendine; Kevin K McCully
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2012-11-15
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  114     ISSN:  1522-1601     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-16     Completed Date:  2013-08-30     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  230-7     Citation Subset:  IM    
Affiliation:
Department of Kinesiology, University of Georgia, Athens, Georgia 30602, USA. tryan7@me.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Electric Stimulation
Exercise / physiology*
Exercise Test
Female
Humans
Male
Mitochondria, Muscle / physiology*
Muscle Contraction / physiology
Muscle, Skeletal / physiology*
Oxygen Consumption / physiology
Physical Exertion / physiology*
Spectroscopy, Near-Infrared*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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