| A comparison of endoscopic and capsule small intestinal biopsy techniques in children with upper gastrointestinal disorders. | |
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MedLine Citation:
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PMID: 8827546 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the adequacy for histological diagnosis and morphometric analysis of small intestinal biopsies obtained by either endoscopic forceps or a capsule technique. METHODOLOGY: Small intestinal biopsies from 176 children were reviewed, 92 obtained by endoscopy and 84 by capsule. RESULTS: The adequacy for making a histological diagnosis was 96 and 81% for endoscopic and capsule biopsies, respectively, and for morphometric analysis it was 86 and 71%. There were more tissue specimens from children who had endoscopic compared with capsule biopsies (2.3 vs 1.8 specimens per patient). CONCLUSIONS: Endoscopic biopsies provide better specimens for histological diagnosis and endoscopy has the advantage of allowing macroscopic assessment of the upper gastrointestinal tract which can be of value in recognizing unexpected pathology and in identifying patchy mucosal changes. |
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Authors:
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M A Eltumi; P S Ong; N D Francis; M J Brueton |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of paediatrics and child health Volume: 32 ISSN: 1034-4810 ISO Abbreviation: J Paediatr Child Health Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-12-13 Completed Date: 1996-12-13 Revised Date: 2007-09-24 |
Medline Journal Info:
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Nlm Unique ID: 9005421 Medline TA: J Paediatr Child Health Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 255-6 Citation Subset: IM |
Affiliation:
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Academic Department of Child Health, Charing Cross and Westminster Medical School, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Biopsy / instrumentation, methods Child Child, Preschool Endoscopes, Gastrointestinal Endoscopy, Gastrointestinal* / methods Gastrointestinal Diseases / diagnosis, pathology* Humans Infant Intestinal Mucosa / pathology* Intestine, Small / pathology Sensitivity and Specificity |
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