| A comparison of the end-tidal sevoflurane concentration for removal of the laryngeal mask airway and laryngeal tube in anesthetized children. | |
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MedLine Citation:
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PMID: 18349182 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: In this study we quantified and compared the optimal sevoflurane concentration required to prevent coughing or moving during or after removal of the laryngeal mask airway (LMA) and the laryngeal tube (LT) in anesthetized children. METHODS: Forty unpremedicated children, aged 8 mo to 12 yr, were randomly allocated to receive the LMA or LT. General anesthesia was induced via mask with sevoflurane and the LMA or LT was inserted. Anesthesia was maintained with sevoflurane and oxygen. At the end of surgery, a predetermined end-tidal sevoflurane concentration was maintained for at least 10 min and the LMA or LT was removed. Using Dixon's up-down method, the concentration for LMA and LT removal was determined by adjusting the dose by a 0.2% increment. Success was defined by the absence of coughing, teeth clenching, gross purposeful movement, breath holding, laryngospasm, and desaturation. RESULTS: The end-tidal concentration of sevoflurane to achieve successful LMA removal in 50% of children was 1.90%, in 95% of children was 2.15%. For the LT, the concentrations were 1.83% and 2.00%. The 50% effective dose values did not differ significantly between groups. CONCLUSIONS: LMA and LT removal in 95% of anesthetized children (aged 8 mo to 12 yr) can be safely accomplished without coughing, moving, or any other airway complications at 0.86 and 0.80 minimum alveolar anesthetic concentration, respectively, and a similar concentration should be used for removal of the LT or LMA in children. |
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Authors:
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Jeong-Rim Lee; Young-Sun Lee; Chong Sung Kim; Seong Deok Kim; Hee-Soo Kim |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 106 ISSN: 1526-7598 ISO Abbreviation: Anesth. Analg. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-19 Completed Date: 2008-04-25 Revised Date: 2009-01-21 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: United States |
Other Details:
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Languages: eng Pagination: 1122-5, table of contents Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology, Seoul National University College of Medicine, Seoul, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia, Inhalation
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methods* Anesthetics, Inhalation / pharmacokinetics* Child Child, Preschool Humans Infant Intubation, Intratracheal* Laryngeal Masks* Methyl Ethers / pharmacokinetics* Safety Tidal Volume |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Inhalation; 0/Methyl Ethers; 28523-86-6/sevoflurane |
| Comments/Corrections | |
Comment In:
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Anesth Analg. 2009 Jan;108(1):379
[PMID:
19095882
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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