Document Detail

A comparison of the effects of EMLA cream and topical 5% lidocaine on discomfort during gingival probing.
MedLine Citation:
PMID:  8934955     Owner:  NLM     Status:  MEDLINE    
This investigation compared the use of a 5% eutectic mixture of local anesthetics (EMLA) cream to a "standard" intraoral topical anesthetic (5% lidocaine) as a means of anesthetizing the gingival sulcus in a double-blind, split-mouth study with human volunteers. A 5-min application of EMLA in a customized intraoral splint resulted in a significant increase in the depth of probing of the gingival sulcus without discomfort compared to a similar application of 5% lidocaine. Following application of EMLA, the pain-free probing depth measured at three sites in the upper premolar region increased by a mean total of 2.8 mm compared to an increase of 1.9 mm with lidocaine. This study suggests EMLA may be advantageous in providing periodontal anesthesia where manipulation of the gingiva is necessary.
D Donaldson; J G Meechan
Related Documents :
9669005 - Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflu...
7452225 - Further evidence for a correlation between eeg synchronization and plasma dbh activity ...
12476815 - Early spay-neuter: clinical considerations.
16465725 - Relationship of bispectral index values, haemodynamic changes and recovery times during...
23315195 - Sources of intravascular atp during exercise in humans: critical role for skeletal musc...
17112675 - Phase relationships support a role for coordinated activity in the indirect pathway in ...
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anesthesia progress     Volume:  42     ISSN:  0003-3006     ISO Abbreviation:  Anesth Prog     Publication Date:  1995  
Date Detail:
Created Date:  1996-12-19     Completed Date:  1996-12-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0043533     Medline TA:  Anesth Prog     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  7-10     Citation Subset:  D    
Department of Oral Medical and Surgical Sciences, University of British Columbia, Vancouver, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Topical
Anesthesia, Dental / methods*
Anesthetics, Local / administration & dosage*
Dental Prophylaxis / methods*
Double-Blind Method
Drug Combinations
Gingiva / drug effects*
Lidocaine / administration & dosage*
Prilocaine / administration & dosage*
Reg. No./Substance:
0/Anesthetics, Local; 0/Drug Combinations; 0/EMLA; 137-58-6/Lidocaine; 721-50-6/Prilocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Lessons from history: Horace Wells and the moral features of clinical contexts.
Next Document:  Flumazenil reversal of conscious sedation induced with intravenous fentanyl and diazepam.