Document Detail


A comparison of coronary angioplasty and coronary artery bypass grafting outcomes in chronic dialysis patients.
MedLine Citation:
PMID:  7847356     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to compare the outcomes of angina, myocardial infarction (MI), cardiac death, and all-cause death following percutaneous transluminal coronary angioplasty (PTCA) or coronary artery bypass grafting (CABG). The study design was based on retrospective, nonrandomized analysis and was set in referral teaching hospitals and community hospitals. Eighty-four chronic dialysis patients with symptomatic coronary artery disease without prior revascularization were included in the study. Twenty-four patients underwent PTCA of one or more vessels, and 60 patients underwent CABG. Recurrence of angina, MI, cardiac death, and all-cause death following revascularization as well as the number of inpatient days preprocedure and postprocedure were recorded. The two patient groups were comparable in terms of age, sex, history of MI, left ventricular mass and function, and angina severity. Diabetes mellitus was more prevalent in the PTCA group. The CABG group had more severe coronary artery disease. The 2-year survival rate of the CABG patients (66%; 95% confidence interval = 53.79) did not differ from that of the PTCA patients (51%; 95% confidence interval = 27.65). Thirteen PTCA patients were restudied 106 +/- 108 days after recurrence of angina; nine (69%) of these patients were found to have angiographic restenosis. The postprocedure risk of angina and the combined endpoints of angina, MI, and cardiovascular death were significantly greater following PTCA than CABG. Percutaneous transluminal coronary angioplasty was the only consistent predictor of outcomes; the adjusted relative risks (compared with CABG) of postprocedure angina and combined endpoints were 16.4 and 10.2, respectively, and were several-fold higher than the unadjusted risks. We conclude that in chronic dialysis patients with symptomatic coronary disease, patients undergoing PTCA have a higher risk of subsequent angina and combined angina, MI, and cardiovascular death than those undergoing CABG. The optimal approach to coronary revascularization in this patient population remains to be determined.
Authors:
A L Rinehart; C A Herzog; A J Collins; J M Flack; J Z Ma; J A Opsahl
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  25     ISSN:  0272-6386     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-03-03     Completed Date:  1995-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  281-90     Citation Subset:  IM    
Affiliation:
Division of Nephrology, Hennepin County Medical Center, School of Medicine and Public Health, Minneapolis, MN 55404.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angina Pectoris / epidemiology
Angioplasty, Transluminal, Percutaneous Coronary* / adverse effects,  mortality
Cause of Death
Chi-Square Distribution
Cohort Studies
Coronary Artery Bypass* / adverse effects,  mortality
Coronary Disease / complications,  mortality,  therapy*
Female
Follow-Up Studies
Humans
Incidence
Kidney Failure, Chronic / complications*,  therapy
Life Tables
Male
Middle Aged
Myocardial Infarction / epidemiology
Prognosis
Proportional Hazards Models
Recurrence
Renal Replacement Therapy*
Retrospective Studies
Risk
Survival Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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