Document Detail

A comparison of combined laparoscopic uterine artery ligation and myomectomy versus laparoscopic myomectomy in treatment of symptomatic myoma.
MedLine Citation:
PMID:  18692826     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the efficacy of uterine artery ligation before laparoscopic myomectomy compared with myomectomy alone. DESIGN: Prospective controlled, clinical trial. SETTING: Private and Shiraz University-affiliated hospitals. PATIENT(S): Of 152 women with symptomatic uterine myomas necessitating surgical intervention who wished to retain their uteri, 65 underwent laparoscopic uterine artery ligation and myomectomy (experimental group) and 87 received laparoscopic myomectomy only (control group). INTERVENTION(S): Ligation of the uterine arteries before laparoscopic myomectomy. MAIN OUTCOME MEASURE(S): Operating time, blood loss, blood transfusion, febrile morbidity, symptoms improvement, recurrence rate, and pregnancy rate. RESULT(S): The average operating time and blood loss were 112 +/- 18 minutes and 173 +/- 91 mL for the experimental group and 95 +/- 14 minutes and 402 +/- 131 mL for the control group, respectively (statistically significant). A total of 15 (17.2%) of the control group patients required a blood transfusion, but none of the experimental group patients required one. Febrile morbidity occurred in 18.5% of the experimental group and 20.7% of the control group. In the experimental group, the recurrence of myoma was 6.2%, and 98.1% of the patients reported symptoms improvement; however, in the control group, these figures were 20.75% and 83.1%, respectively (statistically significant). The pregnancy rates were not statistically significantly different in the experimental group (35%) and the control group (35.7%). CONCLUSION(S): This study demonstrated the superiority of laparoscopic uterine artery ligation combined with myomectomy in treatment of symptomatic myomas.
Saeed Alborzi; Elmira Ghannadan; Soroosh Alborzi; Mehrnoosh Alborzi
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2008-08-09
Journal Detail:
Title:  Fertility and sterility     Volume:  92     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-03     Completed Date:  2009-08-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  742-7     Citation Subset:  IM    
Division of Infertility and Gynecologic Endoscopy, Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran.
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MeSH Terms
Combined Modality Therapy
Gynecologic Surgical Procedures / methods*
Hemostasis, Surgical / methods*
Infertility, Female / etiology,  prevention & control*
Laparoscopy / methods*
Leiomyoma / complications,  surgery*
Middle Aged
Pregnancy Outcome
Treatment Outcome
Uterine Neoplasms / complications,  surgery*
Uterus / blood supply*,  surgery*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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