Document Detail

A comparison of clinical findings of familial Mediterranean fever patients with and without amyloidosis.
MedLine Citation:
PMID:  15290087     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study investigates the clinical and demographic characteristics of familial Mediterranean fever (FMF) patients with and without amyloidosis. PATIENTS AND METHODS: The clinical data of 503 patients with FMF (females:males 250:253) were reviewed. Fifty of these patients had amyloidosis (f:m 23:27). RESULTS: The ages of attack onset in patients with and without amyloidosis were 7.8+/-6.2 and 11.1+/-8.5, respectively (P<0.05). The time between disease onset and diagnosis was longer in patients with amyloidosis than those without (187.6+/-99.4 months and 132.5+/-110.2 months, respectively, P<0.001). More patients in the amyloidosis group had positive family histories of FMF (68% vs 54%, P<0.05). The frequencies of chest pain (78% vs 51%, P<0.001), arthritis ( 80% vs 60%, P<0.01), and erysipelas-like erythema (44% vs 16%, P<0.001) were higher in the amyloidosis group. CONCLUSION: In the amyloidosis group, FMF-related manifestations of chest pain, arthritis, and erysipelas-like erythema are more frequent. Our results also support that long periods between disease onset and diagnosis are associated with a high risk of developing amyloidosis.
Ayse Cefle; Sevil Kamali; Mehmet Sayarlioglu; Murat Inanc; Lale Ocal; Orhan Aral; Meral Konice; Ahmet Gul
Related Documents :
9010967 - Rheumatoid arthritis and bronchiectasis. a retrospective study of fourteen cases.
7300997 - Renal pathology in patients with rheumatoid arthritis.
19609527 - Two cases of distal extremity swelling with pitting oedema in psoriatic arthritis: the ...
705267 - Penicillamine-induced polymyositis-dermatomyositis.
2678247 - Rotator cuff tear: clinical experience with sonographic detection.
24368867 - A pilot study comparing two oxygen delivery methods for patients' comfort and administr...
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2004-07-30
Journal Detail:
Title:  Rheumatology international     Volume:  25     ISSN:  0172-8172     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-09-05     Completed Date:  2005-12-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  442-6     Citation Subset:  IM    
Department of Rheumatology, Division of Internal Medicine, Istanbul University Faculty of Medicine, Istanbul, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age of Onset
Amyloidosis / epidemiology,  etiology*,  pathology
Arthritis / complications,  epidemiology,  pathology
Chest Pain / complications,  etiology,  pathology
Child, Preschool
Erysipelas / complications,  epidemiology,  pathology
Erythema / complications,  epidemiology,  pathology
Familial Mediterranean Fever / complications*,  epidemiology,  pathology
Kidney Failure, Chronic / epidemiology,  etiology,  pathology
Proteinuria / diagnosis,  etiology
Time Factors
Turkey / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Lp(a) lipoprotein and lipids in patients with rheumatoid arthritis: serum levels and relationship to...
Next Document:  Mucinous sweat gland carcinoma of a toe with metastasis to the maxilla. A case report