Document Detail

A comparison between the lecithin/sphingomyelin ratio of Gluck and other phospholipid values of amniotic fluid.
MedLine Citation:
PMID:  808128     Owner:  NLM     Status:  MEDLINE    
We have found the lecithin/sphingomyelin ratio of Gluck (L/S ratio) to be very useful for predicting respiratory distress. It correlated reasonably well with three other phospholipid values: the total lecithin content, the acetone-insoluble lecithin content, and the total lecithin/total phospholipids ratio. When the L/S ratio of amniotic fluid was greater than 2.0 there was no respiratory distress, even if the other phospholipid values indicated that the fetal lungs were still immature.
D O Gebhardt; A Beintema
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  122     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1975 Jul 
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  734-6     Citation Subset:  AIM; IM    
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MeSH Terms
Acetone / analysis
Amniotic Fluid / analysis*
Blood Group Incompatibility
Chromatography, Thin Layer
Infant, Newborn
Phosphatidylcholines / analysis*
Phospholipids / analysis*
Prenatal Diagnosis*
Respiratory Distress Syndrome, Newborn / diagnosis*
Rh-Hr Blood-Group System
Sphingomyelins / analysis*
Reg. No./Substance:
0/Phosphatidylcholines; 0/Phospholipids; 0/Rh-Hr Blood-Group System; 0/Sphingomyelins; 67-64-1/Acetone

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