Document Detail

A comparison between oocyte growth in coculture with granulosa cells and oocytes with granulosa cell-oocyte junctional contact maintained in vitro.
MedLine Citation:
PMID:  512597     Owner:  NLM     Status:  MEDLINE    
Evidence is presented that strongly supports the hypothesis that the junctional association between oocytes and granulosa cells must be maintained to promote oocyte growth and development in vitro and that the coculture of oocytes with granulosa cells is not a sufficient condition for oocyte development. Furthermore, it is shown that incorporation of uridine and leucine by oocytes into TCA-insoluble material is significantly greater in granulosa cell-enclosed oocytes than in cocultured oocytes.
J J Eppig
Related Documents :
6931827 - Heterogeneity of intrafollicular somatic cells and ovulated cumulus masses as evidenced...
20397087 - Cobalt-induced changes in the igf-i and progesterone release, expression of proliferati...
8950607 - Immunolocalization of neurophysin in cytokeratin-positive luteal cells of cows.
9404267 - Follicular growth and ovarian dynamics in mammals.
12690227 - Down-regulation of connexin 32 gene expression through dna methylation in a human renal...
1926137 - Direct cell-cell communication in the blood-forming system.
Publication Detail:
Type:  Comparative Study; In Vitro; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The Journal of experimental zoology     Volume:  209     ISSN:  0022-104X     ISO Abbreviation:  J. Exp. Zool.     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1980-02-28     Completed Date:  1980-02-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375365     Medline TA:  J Exp Zool     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  345-53     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Carbon Dioxide / metabolism
Cells, Cultured
Granulosa Cells / physiology*
Intercellular Junctions / physiology*
Leucine / metabolism
Oocytes / growth & development*,  metabolism
Ovum / growth & development*
Pyruvates / metabolism
Uridine / metabolism
Reg. No./Substance:
0/Pyruvates; 124-38-9/Carbon Dioxide; 58-96-8/Uridine; 61-90-5/Leucine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The interaction of nerves of opposite regenerating polarity in fused newt forelimbs.
Next Document:  Determination of sex by discriminant function analysis of postcranial skeletal measurements.