Document Detail

A comparison of arterial versus venous-activated clotting time in patients with congenital heart disease undergoing cardiac catheterization.
MedLine Citation:
PMID:  10348542     Owner:  NLM     Status:  MEDLINE    
Studies in adult patients undergoing percutaneous coronary angioplasty have demonstrated differences in measured activated clotting time (ACT) in venous vs. arterial blood samples. Ninety-two patients with congenital heart disease undergoing cardiac catheterization were prospectively evaluated to compare venous vs. arterial ACT values in monitoring heparin effect in this population. Simultaneous venous and arterial ACT samples were drawn at baseline, 10 min, 60 min, and every 30 min thereafter until each case was finished. ACT values were determined simultaneously with a dual-chambered Hemochron 801 instrument. At baseline and throughout the study up to 90 min, venous and arterial ACT values were not significantly different. They were also no different in the subgroup of cyanotic patients. Therefore, venous and arterial ACT values can be safely used alternatively to guide heparin dosing during cardiac catheterization in patients with congenital heart disease without the risk of undercoagulation.
B Zeevi; G Bar-Mor; M Livne; M Berant
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  46     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-07-06     Completed Date:  1999-07-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  194-6     Citation Subset:  IM    
Cardiac Catheterization Unit, Schneider Children's Medical Center of Israel, Petah-Tiqva.
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MeSH Terms
Child, Preschool
Heart Catheterization
Heart Defects, Congenital*
Infant, Newborn
Middle Aged
Prospective Studies
Whole Blood Coagulation Time*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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