Document Detail

The comparison of angiographic lesions and clinical outcomes in identical twins.
MedLine Citation:
PMID:  17669944     Owner:  NLM     Status:  MEDLINE    
Both genetic and environmental factors are involved in the development of coronary artery disease (CAD). The degree of contribution of each individual risk factor on CAD is unknown. The extent to which the familial occurrence of coronary heart disease is due to genetic mechanisms can be assessed in twins. In our opinion, due to the chance of mortality risk in monozygotic twin being about 20 times higher than for a representative individual in the overall population, and 3.2- to six-fold higher than for the dizygotic twin of a patient with myocardial infarction, aggressive cardiac evaluation is essential for the asymptomatic twin especially if symptomatic pair's lesion is critical. This report describes similar coronary angiographic findings of identical twins with different coronary risk factors. They both underwent coronary bypass revascularization and had similar uneventful postoperative follow-up.
Ahmet Umit Gullu; Mehmet Kizilay; Mehmet Ates; Murat Akcar
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-04-06
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  6     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-02     Completed Date:  2007-08-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  575-6     Citation Subset:  IM    
Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center, Istanbul, Turkey.
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MeSH Terms
Coronary Artery Bypass
Coronary Artery Disease / genetics*,  radiography,  surgery
Diseases in Twins*
Middle Aged
Twins, Monozygotic*

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