Document Detail

A comparison of the Tzanck smear and viral isolation in varicella and herpes zoster.
MedLine Citation:
PMID:  3006599     Owner:  NLM     Status:  MEDLINE    
We compared the usefulness of the Tzanck smear to viral culture in patients with varicella and herpes zoster. All 11 patients with early lesions of varicella had a positive Tzanck preparation, while only seven (64%) of 11 had a positive culture. Twelve (80%) of 15 patients with zoster had a positive Tzanck preparation, while only nine (60%) of 15 had a positive culture. The predominance of the Tzanck yield over the culture is probably due to the increased difficulty in isolation of the varicella zoster virus. These results suggest that the Tzanck preparation is a valuable tool in the diagnosis of patients with varicella and zoster and offers a much more immediate answer than does viral culture, which often takes one to two weeks. These results contrast with those of our previous study of the Tzanck preparation and herpes simplex, in which the viral culture was more accurate than the Tzanck preparation.
A R Solomon; J E Rasmussen; J S Weiss
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of dermatology     Volume:  122     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-04-10     Completed Date:  1986-04-10     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  282-5     Citation Subset:  AIM; IM    
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MeSH Terms
Chickenpox / diagnosis*,  microbiology
Child, Preschool
Herpes Zoster / complications,  diagnosis*,  drug therapy,  microbiology
Herpesvirus 3, Human / isolation & purification*
Middle Aged

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