Document Detail


A comparison of Hexabrix and Renografin-60 in knee arthrography.
MedLine Citation:
PMID:  3873834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty patients were randomized in a double-blind study to compare the safety and diagnostic quality of Hexabrix vs. Renografin-60 without epinephrine in knee arthrography. Hexabrix is a monoacidic dimer of meglumine and sodium salts of ioxaglic acid with a lower osmolality than conventional contrast agents of similar concentration (32% iodine). Initial films were of equally high diagnostic quality for both groups, but delayed films at 20 and 30 min significantly favored Hexabrix for diagnostic quality. Hexabrix proved to be a safe and effective contrast agent for knee arthrography.
Authors:
J S Apple; S Martinez; M B Khoury; R Royster; S Allen
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  145     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-07-22     Completed Date:  1985-07-22     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  139-42     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Contrast Media* / adverse effects
Diatrizoate / adverse effects,  analogs & derivatives*,  diagnostic use*
Diatrizoate Meglumine / adverse effects,  diagnostic use*
Drug Combinations / adverse effects,  diagnostic use
Female
Humans
Iodobenzoates / diagnostic use*
Ioxaglic Acid
Knee Joint / radiography*
Male
Middle Aged
Triiodobenzoic Acids / adverse effects,  diagnostic use*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Drug Combinations; 0/Iodobenzoates; 0/Triiodobenzoic Acids; 117-96-4/Diatrizoate; 131-49-7/Diatrizoate Meglumine; 59017-64-0/Ioxaglic Acid; 8064-12-8/urovision

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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