Document Detail

A comparison of CW Nd:YAG contact transscleral cyclophotocoagulation with cyclocryopexy.
MedLine Citation:
PMID:  2925323     Owner:  NLM     Status:  MEDLINE    
The cyclodestructive and inflammatory effects of CW Nd:YAG contact laser were compared to those of conventional cryopexy. CW Nd:YAG light transmitted by fiber optic cable and sapphire crystal was applied transsclerally to the ciliary body of pigmented and albino rabbits. Cyclocryopexy was given to a comparable second group. The intraocular pressure (IOP), flare, iritis, cells and conjunctival hyperemia were monitored clinically up to 3 weeks. The breakdown of the blood-aqueous barrier and time course of ocular inflammation was similar for both modalities and IOP was -12.2 +/- 4.2 mm Hg for laser cyclopexy and -15.1 +/- 5.4 mm Hg for cyclocryopexy at 3 weeks. Ciliary body lesions were noted in both groups. Overall, albino rabbits showed less histological damage and faster recovery of IOP. Contact cyclophotocoagulation and cyclocryopexy can be considered models of ocular injury. The similarities in ocular irritative response suggest a similar pathophysiologic mechanism underlying the pressure behavior in both thermal mode injuries.
H D Schubert; J L Federman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  30     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-05-08     Completed Date:  1989-05-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  536-42     Citation Subset:  IM    
Retina Service, Wills Eye Hospital, Philadelphia, PA 19107.
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MeSH Terms
Albinism / pathology,  physiopathology
Ciliary Body / pathology,  surgery*
Eye / pathology,  physiopathology,  radiation effects
Intraocular Pressure / radiation effects
Laser Therapy*
Light Coagulation*
Sclera / radiation effects*

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