Document Detail

A comparative study of preload-adjusted maximal and peak power: assessment of ventricular performance in clinical practice.
MedLine Citation:
PMID:  15601270     Owner:  NLM     Status:  MEDLINE    
This study was performed to determine whether preload-adjusted peak power can act as a surrogate for preload-adjusted maximal power in the assessment of left ventricular performance in the clinical setting. Ninety-nine consecutive patients who had undergone elective coronary artery bypass grafting were studied. Fifty-five of these patients were divided into four study groups. Afterload was changed with phenylephrine (n = 12) or glyceryl trinitrate (n = 13), preload was increased with intravenous colloid (n = 18), and contractility was increased with dobutamine (n = 12). There was excellent correlation between the two indices (r = 0.99, y = 1.0168x + 0.0769; p < 0.0001). Manipulation of neither preload nor afterload affected the indices. Both indices increased significantly during dobutamine infusion (p = 0.002). In conclusion, preload-adjusted peak power can be used as a substitute for preload-adjusted maximal power in the determination of ventricular performance in clinical practice.
R Amà; T Claessens; C Roosens; P Segers; P Verdonck; J Poelaert
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anaesthesia     Volume:  60     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-16     Completed Date:  2005-01-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  35-40     Citation Subset:  AIM; IM    
Institute Biomedical Technology, Ghent University, Ghent, Belgium.
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MeSH Terms
Cardiotonic Agents / diagnostic use
Coronary Artery Bypass*
Dobutamine / diagnostic use
Gelatin / diagnostic use
Hemodynamics / drug effects
Myocardial Contraction
Nitroglycerin / diagnostic use
Phenylephrine / diagnostic use
Postoperative Period
Reproducibility of Results
Ventricular Function, Left* / drug effects
Reg. No./Substance:
0/Cardiotonic Agents; 34368-04-2/Dobutamine; 55-63-0/Nitroglycerin; 59-42-7/Phenylephrine; 9000-70-8/Gelatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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